Stevens, M.D., chief medical officer for Centrexion Therapeutics. CNTX-4975 has the potential to become the first non-surgical approach approved by the FDA to treat Mortons neuroma. With todays announcement of Fast Track designation and the orphan drug designation CNTX-4975 previously received, we are excited to continue building on the momentum of our CNTX-4975 program with the upcoming completion of our Phase 2 open-label, multiple-dose study and initiation of a Phase 3 trial in Mortons neuroma. The FDAs Fast Track process is designed to facilitate the development and expedite the review of drugs used to treat serious conditions and fill an unmet medical need. Fast Track designation enables a company to have early and frequent communication with the FDA throughout the drug development and review process, often leading to earlier drug approval. About Mortons Neuroma Mortons neuroma involves a thickening of the tissue around one of the nerves leading to the toes. This can cause a sharp, burning pain in the foot and stinging, burning or numbness in the toes, especially when walking. Repetitive strain on the front of the foot, such as wearing high-heeled shoes or long-distance running, has been linked to the development of Morton’s neuroma. Although some people can experience relief by switching to lower-heeled shoes with wider toe boxes or by using orthotics, many require medical intervention for the pain. The current standard of care is a corticosteroid injection. If a corticosteroid injection fails, one of the only options is surgery to remove the nerve containing the neuroma, resulting in numb toes at the site of removal.
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In case none of the remedial measures prove to be effective, then it is necessary to consult a doctor, who may prescribe pain killers and antihistamines to reduce the pain and inflammation. Medications: For immediate relief over-the-counter pain relief medications, anti-inflammatory drugs, analgesics, etc., can be used. http://www.heraldsun.com.au/sport/afl/footy-form/dane-swan-will-have-more-surgery-on-broken-foot-nathan-buckley-hopeful-he-will-play-on/news-story/fef678314535c7b8737c4199d25d74abThe individual may have to undergo a series of tests if the pain is unbearable and the swelling has increased considerably. There are a number of causes leading to this condition, the primary one plantar fasciitis. This article provides information regarding the same. Since pain in the feet could be caused due to a variety of reasons, i thought about this the treatment will depend on the underlying cause. In short, it is a movement away from the body and towards the body. Heel pain can reappear and then disappear so the best option is to take proper care of your heel. While calluses may not cause any symptom, corns calluses with a conical shape are usually found to cause pain and discomfort.